World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

COMPARATIVE STUDY BETWEEN BIVENTRICULAR DIASTOLIC DYSFUNCTION IN PATIENTS WITH COPD AND BRONCHIAL ASTHMA DURING EXACERBATION AND STABLE CONDITIONS

Inass M. Taha (MD), Ahmed Abdel Sadek (MD) and Tarek S.Z. Soliman (MD)

ABSTRACT

Objectives: To compare right and left ventricular diastolic dysfunction in patients with chronic obstructive pulmonary disease (COPD) and bronchial asthma patients during exacerbation and in between the attacks. Methods: Thirty patients, 22 males and 8 females, 56 ± 10 years old, with COPD: Group I, were compared to thirty asthmatic patients, 20 males and 10 females, 55 ± 8 years old, Group II. Complete echo-Doppler study and spirometry were done to all patients during exacerbation and in between the attacks. Results: In group I with COPD, right ventricular wall thickness (RVWT), right ventricular end diastolic area (RVEDA) and right atrial area (RAA) were increased significantly in addition to a significant decrease in pulmonary acceleration time (ACT) and ACT/ET ratio (ET: ejection time), compared to asthmatic group II, (P

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