Abstract

Bandi Aiswarya*, Kedem Asha and Dr. K. Thirumala Naik

ABSTRACT

Modern day drug therapy for the control of pain has made great strides in the recent past. Nevertheless, adverse drug reactions, although rare, still remain a major threat to the patient welfare. The drugs involved in the DOT’S therapy (Isoniazid, Rifampicin, Pyrazinamide & Ethambutol) are the most commonly used agents to treat Tuberculosis. But Adverse drug reactions caused by these agents is one of the major concern. It possesses a formidable socio-economic burden on the individual and on the society. Among all ADRS 75 to 80% are classified into type A (predictable) where as 20-25% as type B (unpredictable). I here present a case of 32 years old female patient who was alleged with anti tubercular therapy and presented with complaints of Loss of appetite, Itchy skin, Facial edema and Fever with jaundice, the patient went to local hospital and was further referred to Tertiary Care Teaching Hospital and was diagnosed as Drug induced Hepatitis (Anti Tubercular Therapy) and further management was given to the patient and her condition was improved at the time of discharge .The ultimate goal is always to discontinue the offending medication if possible. Once the offending drug has been identified, it should be promptly discontinued.