World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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SJIF Impact Factor: 6.842

Abstract

THE FETAL TOXICITY OF TRASTUZUMAB (HERCEPTIN) DURING A TWIN PREGNANCY IN BREAST CANCER: ABOUT A CASE

*Dr. K. Diakité, N. Bouzid, S. Zabroug, M. Darfaoui, H. Eddaoualline, N. Ismaili, I. Lalya A. Elomrani, R. Belbaraka and M. Kouchani

ABSTRACT

Breast cancer is the most common solid cancer during pregnancy. Management is a clinical problem because of the fetal risk in case there is an indication for multidrug therapy and the delay in management with a risk of progression during pregnancy. Trastuzumab remains indicated in patients expressing Trastuzumab receptors. The fetal toxicities reported to date are mainly oligohydramnios, respiratory disorders with spontaneous abortion risks. We report the case of a twin pregnancy patient who was exposed to trastuzumab as an adjuvant during her first trimester of pregnancy.

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